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COVERAGE France: A French national adaptative platform trial to evaluate outpatient treatments against COVID-19

Topic:
COVID-19

Sponsor:
Bordeaux University Hospital

Funder:
French Ministry of Health and labeled France National Research Priority

Description

COVERAGE trial is a multicentric adaptative randomized controlled clinical trial plateform evaluating several treatment strategies against COVID19 in outpatients with aggravating risk factors.

Role of EUCLID

  • Methodology
  • Statistical aspects
  • Data management
  • Global coordination of the trial

Publications

Duvignaud, A., Lhomme, E., Pistone, T. et al. Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial). Trials 21, 846 (2020).

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COVERAGE France: A French national adaptative platform trial to evaluate outpatient treatments against COVID-19